Publications
Selected work across my research programme
These selected outputs show how field ecology, environmental stress biology and molecular approaches have developed into questions about biological organisation and resilience.
Selected peer-reviewed publications
Non-model ecotoxicogenomics resource
Escobar-Sierra, C., Hassan, S., Weichert, F. G., Aronsson, H., Lampert, K. P., Hollert, H., Backhaus, T., & Inostroza, P. A. (2025).
De novo transcriptome assembly and annotation of the common freshwater amphipod (Gammarus pulex): a valuable resource for ecotoxicogenomics. Scientific Data, 12, 1502.
DOI
Why it matters: An open molecular resource designed to enable reproducible ecotoxicogenomics in a widely used non-model freshwater sentinel.
Comparative multi-tissue fish transcriptomics
Escobar-Sierra, C., Cañedo-Argüelles, M., Vinyoles, D., & Lampert, K. P. (2024).
Unraveling the molecular mechanisms of fish physiological response to freshwater salinization: A comparative multi-tissue transcriptomic study in a river polluted by potash mining. Environmental Pollution, 357, 124400.
DOI
Why it matters: Connected environmentally realistic exposure with tissue-specific and shared molecular response mechanisms across brain, gill, and liver.
Field-based de novo transcriptomics
Escobar-Sierra, C. & Lampert, K. P. (2024).
Field application of de novo transcriptomic analysis to evaluate the effects of sublethal freshwater salinization on Gasterosteus aculeatus in urban streams. PLOS ONE, 19, e0298213.
DOI
Why it matters: Demonstrated how de novo transcriptomics can recover mechanistic sublethal responses directly from wild fish under complex field conditions.
Multiple-stressor theory
Vos, M., Hering, D., Gessner, M. O., et al., Escobar-Sierra, C., et al. (2023).
The Asymmetric Response Concept explains ecological consequences of multiple stressor exposure and release. Science of the Total Environment, 872, 162196.
DOI
Why it matters: Contributed to a broader conceptual framework for understanding why ecological response to stressor increase and release need not follow the same trajectory.
Ecology meets omics
Escobar-Sierra, C., de Kock, W., Hasler-Sheetal, H., Holmer, M., Chatzigeorgiou, G., Tsapakis, M., & Apostolaki, E. T. (2023).
Metabolomics unravels grazing interactions under nutrient enrichment from aquaculture. Diversity, 15, 31.
DOI
Why it matters: An early integration of ecological experimentation with an omics approach, linking aquaculture-associated nutrient enrichment to community-level metabolic responses.
Software
EchoGO
Escobar-Sierra, C., Langschied, F., Miller, A., & Inostroza, P. A.
Open-source R framework for annotation-context-aware functional interpretation in non-model eco-omics.
Data resources
Gammarus pulex transcriptome resource
An open molecular resource described in the Scientific Data article above. The article DOI is the stable entry point to its data-availability information.
Research compendia
Holtemme Gammarus ecotoxicogenomics research compendium
A versioned reproducible research compendium integrating environmental chemistry, RNA-seq, functional interpretation, and network analysis.
Full publication record
For the complete publication list: